Arizona Cardinals stun Los Angeles Rams, 18–16

The Cardinals closed as 12.5-point underdogs and won outright. The betting market gave them a 16% chance.

All 2026 NFL Week 6 upsets, biggest first

An NFL upset is an underdog getting 3.5 or more points on the closing line winning outright. Upset size is the points it overcame. How it’s scored

1. Arizona Cardinals 18, Los Angeles Rams 16

   12.5-point underdog16% to winRecap
   Upset size12.5
2. Tennessee Titans 26, Indianapolis Colts 20

   6.5-point underdog28% to winRecap
   Upset size6.5