2010 · Week 11 · 4 upsets
Northwestern upsets No. 13 Iowa, 21–17
It was unranked Northwestern taking down the No. 13 team in the AP poll.
All 2010 Week 11 upsets, biggest first
Upset size is the points the winner overcame on the closing line plus a bonus for beating a ranked team. How it’s scored
Northwestern 21, 
No. 13 Iowa 17Upset size6.5
Notre Dame 28, 
No. 15 Utah 3Upset size5.5
USC 24, 
No. 18 Arizona 21Upset size4
Southern Miss 31, 
No. 25 UCF 21Upset size0.5