New York Giants beat Los Angeles Chargers, 21–18

The Giants closed as 6-point underdogs and won outright. The betting market gave them a 29% chance.

It was the biggest of 2 NFL upsets in 2025 Week 4, and the 18th-biggest of the 2025 season. New York Giants pulled off 1 other upset in 2025.

Other NFL upsets in 2025 Week 4

1. Jacksonville Jaguars 26, San Francisco 49ers 21

   3.5-point underdog38% to winRecap
   Upset size3.5

New York Giants’ other 2025 upsets

1. New York Giants 34, Philadelphia Eagles 17

   Week 67-point underdog23% to winRecap
   Upset size7

More: New York Giants upsets · Los Angeles Chargers upsets · all Week 4 upsets · how upset size works