Buffalo Bills stun Cincinnati Bengals, 37–27

The Bills closed as 13-point underdogs and won outright.

It was the biggest of 3 NFL upsets in 2005 Week 16, and the 2nd-biggest of the 2005 season. It was Buffalo Bills's only upset win of 2005.

Other NFL upsets in 2005 Week 16

1. San Francisco 49ers 24, St. Louis Rams 20

   9-point underdogRecap
   Upset size9
2. Dallas Cowboys 24, Carolina Panthers 20

   5.5-point underdogRecap
   Upset size5.5

More: Buffalo Bills upsets · Cincinnati Bengals upsets · all Week 16 upsets · how upset size works