Buffalo upsets Eastern Michigan, 50–31

Buffalo closed as a 6.5-point underdog and won outright.

It was the 10th-biggest of 13 upsets in 2022 Week 4, and the 105th-biggest of the 2022 season. Buffalo pulled off 2 other upsets in 2022.

Other upsets in 2022 Week 4

1. Middle Tennessee 45, No. 25 Miami 31

   25.5-point underdogUnranked beat No. 25Recap
   Upset size26
2. Kansas State 41, No. 6 Oklahoma 34

   13.5-point underdogUnranked beat No. 6Recap
   Upset size23.5
3. Navy 23, East Carolina 20

   16.5-point underdogRecap
   Upset size16.5
4. UTEP 27, Boise State 10

   16.5-point underdogRecap
   Upset size16.5
5. Southern Miss 27, Tulane 24

   11.5-point underdogRecap
   Upset size11.5

Buffalo’s other 2022 upsets

1. Buffalo 34, Toledo 27

   Week 87-point underdogRecap
   Upset size7
2. Buffalo 23, Georgia Southern 21

   Bowl6-point underdogRecap
   Upset size6

More: Buffalo upsets · Eastern Michigan upsets · all Week 4 upsets · the 2022 season · how upset size works