No. 19 Penn State upsets No. 12 Wisconsin, 16–10

Penn State closed as a 5.5-point underdog and won outright. No. 19 beat No. 12 in the AP poll.

It was the 7th-biggest of 16 upsets in 2021 Week 1, and the 77th-biggest of the 2021 season. It was Penn State's only upset win of 2021.

Other upsets in 2021 Week 1

1. Montana 13, No. 20 Washington 7

   22.5-point underdogUnranked beat No. 20FCS beat FBSRecap
   Upset size25.5
2. UC Davis 19, Tulsa 17

   22-point underdogFCS beat FBSRecap
   Upset size22
3. East Tennessee State 23, Vanderbilt 3

   21-point underdogFCS beat FBSRecap
   Upset size21
4. Northern Illinois 22, Georgia Tech 21

   19-point underdogRecap
   Upset size19
5. Utah State 26, Washington State 23

   17-point underdogRecap
   Upset size17

More: Penn State upsets · Wisconsin upsets · all Week 1 upsets · the 2021 season · how upset size works