Wake Forest edges Virginia, 37–17

Wake Forest closed as a 3.5-point underdog and won outright.

It was the 11th-biggest of 13 upsets in 2021 Week 4, and the 154th-biggest of the 2021 season. It was Wake Forest's only upset win of 2021.

Other upsets in 2021 Week 4

1. Bowling Green 14, Minnesota 10

   30.5-point underdogRecap
   Upset size30.5
2. UL Monroe 29, Troy 16

   23.5-point underdogRecap
   Upset size23.5
3. NC State 27, No. 9 Clemson 21

   10.5-point underdogUnranked beat No. 9Recap
   Upset size19
4. Georgia Tech 45, No. 21 North Carolina 22

   14.5-point underdogUnranked beat No. 21Recap
   Upset size17
5. Baylor 31, No. 14 Iowa State 29

   7-point underdogUnranked beat No. 14Recap
   Upset size13

More: Wake Forest upsets · Virginia upsets · all Week 4 upsets · the 2021 season · how upset size works