Indiana edges No. 22 Michigan State, 37–28
It was unranked Indiana taking down the No. 22 team in the AP poll.
Final37–28
Upset size2
Rank in 200145th of 58
It was the 5th-biggest of 5 upsets in 2001 Week 12, and the 45th-biggest of the 2001 season. It was Indiana's only upset win of 2001.
Other upsets in 2001 Week 12
Oregon State 49, 
No. 8 Washington 24Upset size9
NC State 34, 
No. 10 Florida State 28Upset size8
Virginia 39, 
No. 20 Georgia Tech 38Upset size3
No. 24 Auburn 24, 
No. 19 Georgia 17Upset size2.5
More: Indiana upsets · Michigan State upsets · all Week 12 upsets · the 2001 season · how upset size works