College football · NFLTuesday, October 13, 2026
The Upset Report
NFL · 2021 · Week 7 · Sunday, October 24, 2021

Indianapolis Colts beat San Francisco 49ers, 30–18

The Colts closed as 3.5-point underdogs and won outright. The betting market gave them a 39% chance.

Final30–18
Upset size3.5
Chance to win39%
Rank in 202151st of 58

It was the 3rd-biggest of 3 NFL upsets in 2021 Week 7, and the 51st-biggest of the 2021 season. Indianapolis Colts pulled off 1 other upset in 2021.

Other NFL upsets in 2021 Week 7

  1. 6.5-point underdog29% to winRecap
    Upset size6.5
  2. 4-point underdog34% to winRecap
    Upset size4

Indianapolis Colts’ other 2021 upsets

  1. Week 117.5-point underdog26% to winRecap
    Upset size7.5

More: Indianapolis Colts upsets · San Francisco 49ers upsets · all Week 7 upsets · how upset size works